Spryte Medical

Revolutions in neurointerventional imaging, from the discovery of x-rays over 120 years ago, to 3-dimensional imaging in the angiography suite 20 years ago, occur roughly once in a generation. Direct imaging of the pathology and its relationship to devices transforms treatment decisions, and the fundamental understanding of cerebrovascular pathology.

- Matthew Gounis, Ph.D.

The Spryte nOCT Imaging System

Designed to navigate the highly tortuous neurovascular anatomy

Using standard neurovascular workflow, the Spryte nOCT imaging probe brings a micro-optical fiber into the brain’s arteries, allowing for imaging from the inside out. The imaging platform includes an AI-powered console, an optical module, and a fiber-optic, neuroendovascular probe specifically designed to navigate the small, tortuous vasculature of the brain.

The Spryte nOCT technology is an imaging probe that actually works like a wire, and it navigated perfectly through the brain vessels. The system and imaging probes performed very well, integrating with our workflow seamlessly, and provided us with important information that we cannot obtain with any other technology – very impressive.

- Vitor Mendes Pereira, M.D., MSc

nOCT Publications

Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe

Science Translational Medicine, 15 May 2024, Vol 16, Issue 747

Read Article

See More Publications on the Technology

Because of neuro OCT, we will now be able, for the first time, to analyze and better understand different pathologies and the results of our neurointerventional therapies. It is a real game changer in the cerebrovascular field.

- Pedro Lylyk, MD

First in Human Experience with Spryte’s nOCT System

Dr. Vitor Mendes Pereira, St Michael’s Hospital Toronto


About Spryte Medical

Spryte Medical’s mission is to fundamentally transform and improve stroke patient care. Our proprietary AI enabled neuro Optical Coherence Tomography (nOCT) platform is bringing high resolution intravascular imaging inside the brain for the first time. With this approach we can image vessels, disease, and other important structures at >10x the resolution of today’s imaging systems, thus improving clinicians understanding of stroke and other neurovascular disease. In collaboration with our clinical partners we are working to accelerate development of new therapies, enhance procedural techniques and improve patient care worldwide.

Thank You

Our sincere appreciation to our clinical & scientific collaborators for their tremendous dedication toward helping us bring this revolutionary technology to neurovascular patient care.

  • Vania Anagnostakou, MD, MS, PhD
  • Carlos Bleise, MD
  • Nicole M. Cancelliere, MRT(R), MSc
  • Mark Epshtein, PhD
  • Matthew J. Gounis, PhD
  • Ricardo A. Hanel, MD, PhD
  • Robert M. King, PhD
  • Conrad W. Liang, MD, PhD
  • Pedro Lylyk, MD
  • Pedro N Lylyk, MD
  • Ivan Lylyk, MD
  • Demetrius K. Lopes, MD
  • Vitor M. Pereira, MD, MSc
  • Ajit S. Puri, MD, DM, DRE
  • Hidehisa Nishi, MD, PhD
  • Mohammed Salman Shazeeb, PhD
  • Julian Spears, MD, SM, FRCSC, FACS
  • Thomas R. Marotta, MD, FRCPC


We’re growing our team in Bedford, MA, and welcome you to explore our current openings:

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